Buffalo's tech economy includes software, IT services and fintech operations, supported by the University at Buffalo and large regional employers such as M&T Bank. The Buffalo Niagara Medical Campus anchors life-sciences and health IT activity, and the 43North competition has drawn startups to the city.
Top list
Looking for an IT partner in Buffalo, New York? Our 2026 guide ranks the top 10 IT and software companies — with Vayunex Labs as our #1 pick — plus pricing models, a selection checklist and FAQs.